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Molecular Devices, LLC
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    • 제품

      새로운 DispenCell™ Single-Cell Dispenser 기술은 단일 세포주를 3배 더 빠르고 저렴한 비용으로 분리합니다.

      • 쉽고 직관적인 설정
      • 클론형성능과 추적 가능성의 즉각적인 증거
      • 고유한 기술로 세포 샘플을 부드럽게 처리
      • 벤치탑 크기  
        설계
      • 특허받은  
        일회용 팁
      DispenCell™ Single-Cell Dispenser 기술

      최적화된 3D 조직과 오가노이드 실험과정을 위한 BioAssemblyBot의 6축 로봇 팔을 갖춘 자동화된 High-Content Screening 솔루션

      BioAssemblyBot의 6축 로봇 팔

    • Microplate Reader
      SpectraMax Mini Multi-Mode Microplate Reader
      Multi-Mode Reader
      • SpectraMax i3x
      • SpectraMax iD3/iD5
      • SpectraMax M 시리즈
      • FlexStation 3
      • SpectraMax Mini
      SpectraMax ABS 마이크로플레이트
      흡광(Absorbance) 리더기
      • SpectraMax ABS/ABS Plus
      • SpectraMax VersaMax
      • SpectraMax QuickDrop
      • CMax Plus
      Fluorescence Reader
      Fluorescence Reader
      • SpectraMax Gemini
      SpectraMax Luminescence
      발광(Luminescence) 리더기
      • SpectraMax L

       

      MultiWash+ Washer
      Stacker 및 Washer
      • StakMax Stacker
      • AquaMax Washer
      • MultiWash+ Washer
      • MultiWash–C 微孔板洗板机
      SoftMax Pro 데이터 획득
      분석 소프트웨어
      • SoftMax Pro 소프트웨어
      • SoftMax Pro GxP Software
      GxP 솔루션
      GxP Compliance Solution
      • SoftMax Pro GxP Software
      • 소프트웨어 설치와 Validation 서비스
      • IQ/OQ/PM 서비스
      • SpectraTest Validation Plate
      실험실 자동화와 맞춤화
      실험실 자동화와 맞춤화
      • 플레이트 기반 High-Throughput Assay를 위한 실험실 자동화
    • 세포 Imaging 시스템
      ImageXpress Pico Automated Cell Imaging System
      Automated Cell Imaging Systems
      • ImageXpress Pico
      • ImageXpress Nano
      High-Content Imaging
      High-Content Imaging
      • ImageXpress Confocal HT.ai
      • ImageXpress Micro Confocal
      • ImageXpress Micro 4
      StratoMineR 분석
      Acquisition & Analysis Software
      • IN Carta
      • StratoMineR
      • MetaXpress
      • CellReporterXpress
      • MetaMorph
      실험실 자동화와 맞춤화
      실험실 자동화와 맞춤화
      • High-Throughput, High-Content Screening(HCS)을 위한 실험실 자동화
      • BioAssemblyBot 400 Bioprinter 자동화 HCS 솔루션
    • 클론 스크리닝
      Clone Pix 시리즈
      포유류 콜로니 피킹
      • ClonePix 2
      QPix 미생물 콜로니 피커
      미생물 콜로니 피킹
      • QPix 420
      • QPix 450/460
      • QPix HT
      CloneSelect Imager FL
      단일 세포 Imaging
      • CloneSelect Imager
      • CloneSelect Imager FL
      DispenCell Single-Cell Dispenser
      단일 세포 분리
      • DispenCell Single-Cell Dispenser
      실험실 자동화
      실험실 자동화와 맞춤화
      • High-Throughput 클론 스크리닝을 위한 실험실 자동화
      CloneMedia와 XP Media
      배지 및 시약
      Clone Screening Assay kit
      Clone Screening Assay kit
    • FLIPR Penta
      FLIPR Penta
      FLIPR Penta
      • FLIPR Penta High-Throughput 세포 스크리닝 시스템
      Screenworks
      분석 소프트웨어
      • ScreenWorks 소프트웨어
      • Peak Pro 2 소프트웨어 모듈
      Flipr Assay 키트
      FLIPR Assay 키트
      • 칼슘 Assay 키트
      • 칼륨 분석 키트
      • 막전위 분석키트
      • EarlyTox 심장 독성 키트
    • Axon Patch-Clamp
      투명
      Amplifier
      • Axopatch 200B 콘덴서
      • MultiClamp 700B
      • Axoclamp 900A
      투명
      Digitizer
      • Axon Digidata 1550B Low
      투명
      분석 소프트웨어
      • pCLAMP 11 소프트웨어 제품군
    • 기타
      Threshold Immunoassay System
      Threshold Immunoassay System
      Geneppix 미세배열 스캐너
      Genepix 미세배열 스캐너
      Imagexpress Micro Xls
      Imagexpress Micro xls
      인증 리퍼브
      인증 리퍼브
      IDBS 솔루션
      IDBS R&D 클라우드 솔루션
    • 분석 시약(assay kit)
      심장 독성
      • EarlyTox 심장 독성 키트
      Cell viability
      • EarlyTox Cell Integrity Kit
      • EarlyTox Cell Viability Assay Kit
      DNA 정량 분석
      • Spectramax Quant dsDNA Assay 키트
      Elisa, western blot
      • CatchPoint SimpleStep ELISA 키트
      • ScanLater Western Blot Assay 키트
      gpcr
      • FLIPR 칼슘 Assay 키트
      • Fura-2 QBT 칼슘 키트
      • CatchPoint cAMP 형광 Assay 키트
      • CatchPoint cGMP 형광 Assay 키트
      이온 통로
      • FLIPR 칼륨 Assay 키트
      • FLIPR 막전위 Assay 키트
      IGG 정량분석
      • ValitaTiter
      • CloneDetect
      Reporter gene
      • Spectramax Glo Steady-Luc Reporter Assay Kit
      • Spectramax DuoLuc Reporter Assay Kit
      Transporter
      • QBT Fatty Acid Uptake Assay Kit
      • 신경전달물질 수송체 흡수 Assay 키트
      기타
      • Contamination Detection
      • Enzyme - IMAP Assay
    • 액세서리 및 소모품
      Microplate Reader
      • 384 Well SBS
      • 384 Well High Sample Recovery Plate
      • Deep-well Plate
      • Low Profile Microplate
      • SpectraDrop Micro-Volume Microplate
      • SpectraMax Injection cartridge with SmartInject Technology
      • SpectraMax MiniMax 300
        Imaging Cytometer
      • Western Blot Cartridge
      • 96孔微孔板
      클론 스크리닝
      • Adjustable Petri Dish and Microplate Holder
      • Bioassay QTrays
      • Calibead
      • 캡 매트 및 뚜껑
      • 크로마 필터
      • 세정 및 살균 솔루션
      • CloneSelect Single-Cell Printer Cartridge
      • QPix 핀 및 헤드
      • QReps 레플리케이터
      Axon Patch-Clamp
      • Soft Panel Amplifier Control
      Spectra Img
  • 연구 분야
    • 응용 분야

      Molecular Devices, Cellesce 인수로 환자 유래 오가노이드 특허 기술 추가

      2022년 12월 6일

      • Cellesce의 동종 업계 최초 기술로 대규모 약물 Screening을 위한 일관적인 환자 유래 오가노이드를 생성합니다.
      • 인수를 통해 Molecular Devices의 3D 생물학 솔루션 혁신 기업으로서의 입지를 강화합니다.
      • 결합된 전문 지식으로 신약 개발을 위해 생리학적으로 연관된 세포 모델의 채택을 업계에서 가속화할 것입니다.

       

      OIC 방문하기

      언론 보도 읽기

      Cellsce
      응용 분야를 위한 Spectra
    • 코로나바이러스 (COVID-19)
      코로나19
      코로나19 연구
      관련 솔루션
      코로나19
      코로나19 관련
      새로운 뉴스
      코로나19
      백신 개발 워크플로
      감염병 연구 응용 분야
      백신 연구
      연구 응용 분야
    • 연구분야 (Stem Cell, Cancer)
      투명
      3D Cell Model
      투명
      암 연구 솔루션
      투명
      Cell Line Development
      투명
      신약 개발
      투명
      식품 및 음료
      투명
      유전자 편집(CRISPR/Cas9)
      투명
      오가노이드 연구
      투명
      줄기세포 연구
      투명
      독성학
    • Microplate Reader
      투명
      세포 건강 상태 (Cell Health)
      투명
      Cellular Signaling
      투명
      ELISA
      투명
      미생물학과 오염물질
      투명
      핵산(DNA/RNA) 측정과 분석
      투명
      단백질 측정, 정량분석, 분석
      투명
      관련 분석법: 측정 모드
      • 흡광(Absorbance)
      • 형광(Fluorescence)
      • 형광 편광
      • 발광(Luminescence)
      • TRF, TR-FRET 및 HTRF
      • Western Blot
    • 세포 Imaging 시스템
      투명
      Cell Counting
      투명
      세포 이미징 및 분석
      투명
      세포 Migration Assay
      투명
      세포 염색
      투명
      Live Cell Imaging
      투명
      Neurite Outgrowth
      투명
      장기 칩
      투명
      오가노이드
      투명
      Spheroids
    • 클론 스크리닝
      투명
      Cell line development 실험과정
      투명
      단클론항체(mAb)
      • 하이브리도마
      • 파지 디스플레이
      • 단일클론항체 생산
      투명
      Monoclonality
      투명
      합성 생물학
    • FLIPR Penta
      투명
      GPCR(G protein-coupled receptor)
      투명
      이온 채널
      투명
      Cardiotoxicity(심장독성)
    • Axon Patch-Clamp
      투명
      전기생리학(Patch Clamp)
  • 자료
    • 자료
    • 관련 자료 검색
      메뉴 자료 아이콘/응용 분야 노트
      Application Note
      메뉴 자료 아이콘/레퍼런스
      레퍼런스
      Ebook 아이콘
      eBook
      메뉴 자료 아이콘/Scientific Poster
      Scientific Poster
      메뉴 자료 아이콘/튜토리얼 및 영상
      동영상 및 웨비나

      검색

    • 블로그 – 실험실 노트
      스페이서
      Assay에 대한 고객 사례…
      스페이서
      3D organoids and…
      How 3D Cell Models Will Shape the Future of Drug Discovery
      2023년 3월 7일 Target discovery and drug development rely heavily on 2D cell and animal models to decipher efficacy and toxic effect of drug candidates. Yet, 90% of candidates fail to…
      더 알아보기  
    • 고객 사례 소개

      다른 연구자들이 제품과 솔루션을
      어떻게 사용했는지 확인해보세요.

    • 혁신 기술
      투명
      AI, 머신러닝 및 딥러닝
      투명
      AgileOptix 스피닝 디스크 기술
      투명
      자동 초점
      투명
      디지털 공초점 옵션
      투명
      고함량 Screening
      투명
      HumSilencer
      투명
      레이저 조명
      투명
      QuickID 표적 이미지 획득
    • 관련 분석법
      투명
      흡광(Absorbance)
      투명
      전기생리학
      투명
      형광(Fluorescence)
      투명
      형광 편광(FP)
      투명
      발광(Luminescence)
      투명
      TRF, TR-FRET 및 HTRF
      투명
      Water Immersion Objective
      투명
      Western Blot
    • 동영상 갤러리
      투명
      Microplate Reader
      투명
      세포 Imaging 시스템
      투명
      Flipr 시스템
      투명
      클론 스크리닝
      투명
      Axon Patch-Clamp
      투명
      주문형 웨비나
  • 서비스 및 지원
    • 서비스 및 지원
    • 개요
      Spectra 로고
      SpectraNet 고객 관리 포털
      GxP 컴플라이언스
      GxP 컴플라이언스 솔루션
      실험실 자동화와 맞춤화
      실험실 자동화와 맞춤화
      전문 서비스
      전문 서비스

      기술 지원

      미국 본사  
      +1 800-635-5577  
      월~금, 오전 7시~오후 5시 PST

      유럽  
      +44-118-944-8000  
      월~금, 오전 8시~오후 5시 GMT

      내가 있는 지역의 담당자 확인하기

      SpectraNet 고객 포털  

    • 고객 포털 - Spectranet
      Spectranet

      INTRODUCING OUR NEW CUSTOMERCARE PORTAL

      SpectraNet is an intuitive, simple-to-use, self-service customer portal providing a new level of experience available 24/7.

      Create your account today to get full access to integrated content and world-class customer service.

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    • GxP 컴플라이언스 솔루션
      GxP Softmax Pro GxP 소프트트웨어
      SOFTMAX PRO GXP 소프트웨어
      GxP 소프트웨어 설치
      소프트웨어 설치와 Validation 서비스
      GxP Spectratestt Validation Plate 재인증
      SPECTRATEST Validation Plate
      IQ OQ 서비스
      IQ/OQ/PM 서비스
    • 실험실 자동화
      실험실 자동화와 맞춤화
      실험실 자동화와 맞춤화
      High Content Screening HCS
      High-Throughput, High-Content Screening
      • BioAssemblyBot 400 Bioprinter 자동화 HCS 솔루션
      플레이트 기반 High-Throughput Assay
      플레이트 기반 High-Throughput Assay
      High-Throughput 클론 스크리닝
      High-Throughput 클론 스크리닝
    • 전문 서비스
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  • 회사
    • 회사

      Molecular Devices, 오스트리아의 글로벌 R&D 허브 확장

      2022년 10월 12일        
      더 큰 부지는 Cell Line Development, 오가노이드 개발, 신약 개발을 개선하기 위한 Screening 솔루션을 발전시키기 위한 협업 공간인 잘츠부르크의 오가노이드 혁신 센터의 미래 기지가 될 것입니다.

       

      OIC 방문하기

      언론 보도 읽기

      Austrian Research & Development Center의 리본 커팅 기념식
      응용 분야를 위한 Spectra
    • 회사 소개

      Molecular Devices는 실리콘 밸리를 기반으로 제약 및 연구의 스크리닝과 효과적인 분석이 가능한 솔루션을 30년에 걸쳐 개발하고 공급해 왔습니다.

    • 리더십
      Molecular Devices 리더십
    • 채용

      당사의 팀 중심 기업 문화는 생각과 관점의 다양성과 강력한 신뢰 관계를 보장합니다.

    • 뉴스룸
      투명
      뉴스
      투명
      보도 내용
      Silver Sponsor Molecular Devices at Society for Laboratory Automation and Screening 2023 International Conference and Exhibition
      Feb 22, 2023 Showcasing new industry collaborations, automated technology, and workflow innovations that span 3D biology, cell line development, and drug…
      Read more  
    • 이벤트
      Focus on Microscopy (FOM)
      Conference | Europe | Porto, Portugal, Europe– Apr 02 – Apr 5, 2023 FOM2023 continues a long-standing (since 1988), yearly conference series on the latest innovations and developments in (optical) microscopy and their…
      Read more  
      Imaging User Meeting 2023
      Conference | Europe | Copenhagen, Denmark– May 09 – May 10, 2023 Ideal for both current ImageXpress system users and those wanting to learn more about high-content, high-throughput, automated or 3D imaging, our…
      Read more  
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  1. Home
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  4. Get to know our Field Applications Scientist: Dwayne Carter
Molecular Devices Lab Notes

Get to know our Field Applications Scientist: Dwayne Carter

  • January 18, 2021
  • Dwayne Carter, PhD | BioPharma Field Applications Scientist

Dwayne Carter gives us a taste of 3D bioprinting, clone screening, and Caribbean cuisine

Dwayne Carter is a cell biologist and educator who joined Molecular Devices in November 2020. We asked Dwayne to tell us more about his background, career milestones, current role, and the future he envisions for clone screening.

Dwayne


Dwayne, please tell us bit about your background.

I am originally from the Caribbean island of Grenada. There, I started my career teaching mathematics. I relocated from Grenada to Wichita Falls, Texas to pursue my undergraduate degree in biology and chemistry. It was during this time that I was introduced to bioresearch working as a laboratory assistant. After obtaining my bachelor’s degree, I taught high school level chemistry over the next four years. I then moved on to graduate school at the University of Texas Medical Branch in Galveston, where I studied cell biology with an emphasis on liver biology. In particular, I studied how transcription factors play a role in xenobiotic metabolism (i.e., the metabolism of air pollutants). My training in liver biology led me to complete my post doc at a company in San Diego called Organovo. There I worked on engineering 3D bioprinted liver tissues.

 


What are 3D bioprinted tissues and how do they differ from organoids?

Organoids are 3D structures that are derived from stem cells or cells from a certain region within an organ. The cells are cultured with different growth factors/stimuli so that they can differentiate into the cell types that are representative of the functional cells within a particular organ.

Unlike organoids, 3D bioprinted tissues are derived from cells of a cadaver (i.e., terminally differentiated cells). Basically, you assemble cells into different geometries within a dish. The cells will then coalesce and function in a manner that is similar to normal tissue physiology. For instance, they can release cytokines and hormones and have similar cell-cell interactions to what we observe with in vivo biology. In essence, you are using printing technology to put cells in a configuration that will allow them to function and have some of the phenotype of an actual organ.

3D bioprinted tissues

Register to view our webinar collaboration with Greiner Bio-One, Magnetic 3D Bioprinting, 3D Cell Culture in a 2D Workflow


Although they differ somewhat, the ultimate goal for both of these 3D cellular models is to help researchers advance their studies in drug efficacy and toxicity.

 

So how did you arrive at Molecular Devices and tell us about your current role?

Prior to arriving at Molecular Devices, I worked as a principal scientist at Emulate Biosciences in Boston, where I studied another emerging 3D cellular model called organ-on-a-chip technology. At Emulate, I had the opportunity to spend some time in the field and train users on the technology. The company realized that I really had a knack for training customers, and they transitioned me over to a Field Applications Scientist role, which eventually led me to Molecular Devices, where I’ve been working since November of last year.

I am a BioPharma Field Applications Scientist covering the southern region of the United States. In this role, I provide pre- and post-sale product training and scientific support for our portfolio of clone screening systems. This involves answering questions about our technology and giving presentations and/or webinars to support the sales team. I also train users after they have purchased our instruments.

 

What do you think makes the role of a Field Applications Scientist unique?

I think the role of a Field Applications Scientist is unique in that we have the hands-on experience of working in the lab and conducting experiments using the technology. We understand all of the different intricacies of the technology and the “tricks of the trade” that are needed to help customers drive their experiment toward a successful completion.

In addition to having that hands-on scientific and technology expertise, we are able to apply our teaching skills to help customers meet their goals. For me, the key is being patient and having the ability to adapt to different learning styles.

 

How do you overcome the challenges of training customers remotely during COVID?

Because our clone screening systems are pretty intuitive, they eliminate a lot of the hurdles associated with training first-time users. Our field engineers will typically go to the customer site to install the system hardware and software and ensure that it is fully operational in preparation for the customer training. Once the system is installed, the software is similar to a wizard in that it presents users with a series of steps or questions to help guide them on how to run the instrument and perform analysis. Likewise, the hardware is designed in such a manner that makes it easy for the user to change out or install certain components. This provides customers the comfort level to be trained remotely and get up and running quickly.

 

What excites you most about Molecular Devices and our portfolio of clone screening systems?

I am really excited by our commitment to continually innovate and meet the present and future needs of our customers. We provide them hardware and software solutions to address every phase of their workflow and ensure that they experience the most success. Our Customization and Automation team can work with them to help integrate robotics into our systems so that they can increase their walkaway time and spend time on more critical tasks.

Qpix Overview Video

 

What are some of the emerging applications for clone screening?

I think clone screening will play a significant role in drug discovery. There is a huge translational and productivity challenge in the drug development process. It typically takes 10-15 years for a drug to go from inception to reaching the market. The challenge is that there is no good way to predict how the drug will perform in the clinic. Also, the processes to validate drug efficacy and safety are very cumbersome and require a lot of FTE hours. That being said, there is a growing push for tissue engineering so that we can model organs or systemic diseases in vitro and have something that is more predictive than the traditional animal models. We can get iPSC-differentiated cells and use cloning techniques like CRISPR to engineer those cells to produce organs that are more representative of the population that we are interested in.

This then leads to personalized medicine. Here, we focus on a patient’s cells to design treatments that have a mode of action that is more targeted to his/her metabolic profile. Due to the co-morbidities, diet, environment, and other surrounding factors that make the disease different, clone screening can help speed up the drug development process.

Lastly synthetic biology is being used to engineer existing biology to take on new functions. For example, biology can be re-engineered to create biofuels, foods for consumption, new drugs, and systems to improve quality of life. I think clone screening will also play a significant role in this field.

 

What advancements do you envision for clone screening over the next few years?

I would envision the ability to create fully automatable systems that can address any problem involving clone screening, antibody discovery or cell line development. This will make the drug development process more efficient, especially as it relates to personalized medicine.

 

What do you enjoy doing in your spare time?

I enjoy spending time with my family. I have two young children. My son (age 5) has autism, and my daughter (age 6) is in a gifted and talented program. I enjoy seeing them both develop and grow in their own unique way. Whenever I have a chance to connect virtually with my buddies who are spread across the U.S., we play video games. I also enjoy listening to country music and upcycling my thrift store finds into something new and unique. Lastly, I have to admit that one of my favorite hobbies is eating Caribbean food!

 

What is your favorite Caribbean food?

My favorite food is doubles.

Doubles are basically two flatbreads that are filled with channa (i.e., curried chickpeas). To prepare the flatbreads, you mix flour, curry powder, yeast, water, and vegetable oil into a dough. Then divide the dough into small round pieces and deep fry them until puffy and golden. Then place the channa between the two flatbreads and serve them with a sweet tamarind sauce. If possible, I would eat doubles every day of the week. They are absolutely delicious!

 

doubles

To learn more about our solutions for antibody discovery and cell line development, visit our clone screening systems page.

 

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