SCIENTIFIC POSTER
Scalable patient-derived 3D colorectal cancer organoids in high throughput applications
Organoid technology holds significant promise in transforming drug discovery.
https://vids.moleculardevices.com/watch/gaZUHrvGEnYf2yRKXjkDLx
The combination of large-scale organoid production with automation-based screening workflows will help overcome some of the current barriers to organoid use.
In this poster, we used a semi-automated process for the controlled large-scale production of uniform, assay-ready organoids to generate image-based readouts along with morphological profiling to help understand complex phenotypes associated with PDOs. Our results demonstrate the utility of PDOs in high-throughput drug discovery applications using automation with high-content imaging.