Automated dispensing, monitoring, and assay development of hydrogel-based cellular models

Increase hydrogel-based cellular model assay throughput and reduce cost with automated liquid handling and high-content imaging

Cellular models that more precisely represent various microenvironments are incredibly important for accurate drug screening and disease modeling. They can be used as in vitro and in vivo models to conduct high-throughput, cost-effective assays that are vital to discovering biologically relevant therapies.

In this application note, we describe a method using patient-derived triple-negative breast cancer cells in conjunction with an automated dispense pipette tool to create hydrogel-based cellular models to observe cell growth and evaluate drug efficacy.